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Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy
Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular Dystrophy (DMD). To date, glucocorticoids remain the gold standard for the treatment of DMD. These drugs are able to slow down the p...
Autores principales: | Dort, Junio, Orfi, Zakaria, Fabre, Paul, Molina, Thomas, Conte, Talita C., Greffard, Karine, Pellerito, Ornella, Bilodeau, Jean-François, Dumont, Nicolas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556273/ https://www.ncbi.nlm.nih.gov/pubmed/34716330 http://dx.doi.org/10.1038/s41467-021-26516-0 |
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