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A curated diverse molecular database of blood-brain barrier permeability with chemical descriptors

The highly-selective blood-brain barrier (BBB) prevents neurotoxic substances in blood from crossing into the extracellular fluid of the central nervous system (CNS). As such, the BBB has a close relationship with CNS disease development and treatment, so predicting whether a substance crosses the B...

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Detalles Bibliográficos
Autores principales: Meng, Fanwang, Xi, Yang, Huang, Jinfeng, Ayers, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556334/
https://www.ncbi.nlm.nih.gov/pubmed/34716354
http://dx.doi.org/10.1038/s41597-021-01069-5