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Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity

Activation of adipose tissue macrophages (ATMs) contributes to chronic inflammation and insulin resistance in obesity. However, the transcriptional regulatory machinery involved in ATM activation during the development of obesity is not fully understood. Here, we profiled the chromatin accessibility...

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Detalles Bibliográficos
Autores principales: Hu, Ren-Dong, Zhang, Wen, Li, Liang, Zuo, Zu-Qi, Ma, Min, Ma, Jin-Fen, Yin, Ting-Ting, Gao, Cai-Yue, Yang, Shu-Han, Zhao, Zhi-Bin, Li, Zi-Jun, Qiao, Gui-Bin, Lian, Zhe-Xiong, Qu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556336/
https://www.ncbi.nlm.nih.gov/pubmed/34716308
http://dx.doi.org/10.1038/s41419-021-04308-0