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Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma

Cholangiocarcinomas (CCAs) are rare but aggressive tumors of the bile ducts. CCAs are often diagnosed at an advanced stage and respond poorly to current conventional radiotherapy and chemotherapy. High mobility group A1 (HMGA1) is an architectural transcription factor that is overexpressed in multip...

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Detalles Bibliográficos
Autores principales: Song, Jianping, Cui, Donghai, Wang, Jing, Qin, Junchao, Wang, Shourong, Wang, Zixiang, Zhai, Xiangyu, Ma, Huan, Ma, Delin, Liu, Yanfeng, Jin, Bin, Liu, Zhaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556338/
https://www.ncbi.nlm.nih.gov/pubmed/34716319
http://dx.doi.org/10.1038/s41420-021-00721-8