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Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma
Cholangiocarcinomas (CCAs) are rare but aggressive tumors of the bile ducts. CCAs are often diagnosed at an advanced stage and respond poorly to current conventional radiotherapy and chemotherapy. High mobility group A1 (HMGA1) is an architectural transcription factor that is overexpressed in multip...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556338/ https://www.ncbi.nlm.nih.gov/pubmed/34716319 http://dx.doi.org/10.1038/s41420-021-00721-8 |