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Nrf2 attenuates ferroptosis-mediated IIR-ALI by modulating TERT and SLC7A11

Acute lung injury (ALI) carries a mortality rate of ~50% and is a hot topic in the world of critical illness research. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical modulator of intracellular oxidative homeostasis and serves as an antioxidant. The Nrf2-related anti-oxidative stres...

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Detalles Bibliográficos
Autores principales: Dong, Hui, Xia, Yangyang, Jin, Shanliang, Xue, Chaofan, Wang, Yanjun, Hu, Rong, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556385/
https://www.ncbi.nlm.nih.gov/pubmed/34716298
http://dx.doi.org/10.1038/s41419-021-04307-1