Statin-mediated disruption of Rho GTPase prenylation and activity inhibits respiratory syncytial virus infection

Respiratory syncytial virus (RSV) is a leading cause of severe respiratory tract infections in children. To uncover new antiviral therapies, we developed a live cell-based high content screening approach for rapid identification of RSV inhibitors and characterized five drug classes which inhibit the...

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Detalles Bibliográficos
Autores principales: Malhi, Manpreet, Norris, Michael J., Duan, Wenming, Moraes, Theo J., Maynes, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556396/
https://www.ncbi.nlm.nih.gov/pubmed/34716403
http://dx.doi.org/10.1038/s42003-021-02754-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556396/
https://www.ncbi.nlm.nih.gov/pubmed/34716403
http://dx.doi.org/10.1038/s42003-021-02754-2

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