Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux

Perturbations to cellular homeostasis, including reduction of the cholesterol level, induce autophagy, a self-digestion process of cellular constituents through an autophagosomal–lysosomal pathway. In accord with its function as a membrane organizer and metabolic sentinel, the cellular response to c...

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Detalles Bibliográficos
Autores principales: Shapira, Keren E., Shapira, Guy, Schmukler, Eran, Pasmanik-Chor, Metsada, Shomron, Noam, Pinkas-Kramarski, Ronit, Henis, Yoav I., Ehrlich, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556405/
https://www.ncbi.nlm.nih.gov/pubmed/34716312
http://dx.doi.org/10.1038/s41420-021-00718-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556405/
https://www.ncbi.nlm.nih.gov/pubmed/34716312
http://dx.doi.org/10.1038/s41420-021-00718-3

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