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Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux
Perturbations to cellular homeostasis, including reduction of the cholesterol level, induce autophagy, a self-digestion process of cellular constituents through an autophagosomal–lysosomal pathway. In accord with its function as a membrane organizer and metabolic sentinel, the cellular response to c...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556405/ https://www.ncbi.nlm.nih.gov/pubmed/34716312 http://dx.doi.org/10.1038/s41420-021-00718-3 |