Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet

Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of lipid droplets in hepatocytes. NAFLD development and progression is associated with an increase in hepatic cholesterol levels and decreased autophagy and lipophagy flux. Previous studies have shown that the expression o...

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Detalles Bibliográficos
Autores principales: Lopresti, Michael W., Cui, Wenqi, Abernathy, Breann E., Fredrickson, Gavin, Barrow, Fanta, Desai, Arnav S., Revelo, Xavier S., Mashek, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556525/
https://www.ncbi.nlm.nih.gov/pubmed/34624333
http://dx.doi.org/10.1016/j.jlr.2021.100133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556525/
https://www.ncbi.nlm.nih.gov/pubmed/34624333
http://dx.doi.org/10.1016/j.jlr.2021.100133

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