A Hypothalamic-Controlled Neural Reflex Promotes Corneal Inflammation

PURPOSE: To test whether an acute corneal injury activates a proinflammatory reflex, involving corneal sensory nerves expressing substance P (SP), the hypothalamus, and the sympathetic nervous system. METHODS: C57BL6/N (wild-type [WT]) and SP-depleted B6.Cg-Tac1tm1Bbm/J (TAC1-KO) mice underwent bila...

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Detalles Bibliográficos
Autores principales: Lasagni Vitar, Romina Mayra, Fonteyne, Philippe, Chaabane, Linda, Rama, Paolo, Ferrari, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556564/
https://www.ncbi.nlm.nih.gov/pubmed/34698773
http://dx.doi.org/10.1167/iovs.62.13.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556564/
https://www.ncbi.nlm.nih.gov/pubmed/34698773
http://dx.doi.org/10.1167/iovs.62.13.21

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