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Development of a recombinant vaccine containing a spike S1-Fc fusion protein induced protection against MERS-CoV in human DPP4 knockin transgenic mice

The Middle East respiratory syndrome coronavirus (MERS-CoV), belonging to the family Coronaviridae and genus Betacoronavirus, has been recognized as a highly pathogenic virus. Due to the lack of therapeutic or preventive agents against MERS-CoV, developing an effective vaccine is essential for preve...

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Detalles Bibliográficos
Autores principales: Jung, Bo-Kyoung, An, YongHee, Park, Jung-Eun, Chang, Kyung-Soo, Jang, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556695/
https://www.ncbi.nlm.nih.gov/pubmed/34728273
http://dx.doi.org/10.1016/j.jviromet.2021.114347