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Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen

BACKGROUND: Viral vectors, including adenovirus (Ad) and modified vaccinia Ankara (MVA), have gained increasing attention as vaccine platforms in recent years due to their capacity to express antigens from a wide array of pathogens, their rapid induction of humoral and cellular protective immune res...

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Detalles Bibliográficos
Autores principales: Sheerin, Dylan, Dold, Christina, O’Connor, Daniel, Pollard, Andrew J., Rollier, Christine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556829/
https://www.ncbi.nlm.nih.gov/pubmed/34717548
http://dx.doi.org/10.1186/s12864-021-08061-8