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Doxorubicin inhibits osteosarcoma progression by regulating circ_0000006/miR-646/ BDNF axis

BACKGROUND: Osteosarcoma (OS) is the most common aggressive bone tumor in children and teenagers. Doxorubicin (DOX) is a chemotherapeutic drug for OS. This study aims to reveal the effects and underneath mechanism of DOX treatment in OS progression. METHODS: The expression of circular_0000006 (circ_...

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Detalles Bibliográficos
Autores principales: Amuti, Abulimiti, Liu, Dehu, Maimaiti, Ayiguli, Yu, Yao, Yasen, Yalikun, Ma, Haoguang, Li, Rui, Deng, Shurong, Pang, Fei, Tian, Youliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557021/
https://www.ncbi.nlm.nih.gov/pubmed/34717683
http://dx.doi.org/10.1186/s13018-021-02782-y