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Solvent Effects on Skin Penetration and Spatial Distribution of the Hydrophilic Nitroxide Spin Probe PCA Investigated by EPR

Oxidative stress occurs in extrinsic skin aging processes and diseases when the enhanced production of free radicals exceeds the homeostatic antioxidant capacity of the skin. The spin probe, 3-(carboxy)-2,2,5,5-tetramethylpyrrolidin-1-oxyl (PCA), is frequently used to study the cutaneous radical pro...

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Detalles Bibliográficos
Autores principales: Dong, Pin, Teutloff, Christian, Lademann, Jürgen, Patzelt, Alexa, Schäfer-Korting, Monika, Meinke, Martina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557165/
https://www.ncbi.nlm.nih.gov/pubmed/32303897
http://dx.doi.org/10.1007/s12013-020-00908-3