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Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling

PURPOSE: Menopause is associated with an increased risk of estrogen receptor-positive (ER +) breast cancer. To characterize the metabolic shifts associated with reduced estrogen bioavailability on breast tissue, metabolomics was performed from ovary-intact and ovariectomized (OVX) female non-human p...

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Detalles Bibliográficos
Autores principales: Arnone, Alana A., Cline, J. Mark, Soto-Pantoja, David R., Cook, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557185/
https://www.ncbi.nlm.nih.gov/pubmed/34448090
http://dx.doi.org/10.1007/s10549-021-06354-w