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Investigating the role of endogenous estrogens, hormone replacement therapy, and blockade of estrogen receptor-α activity on breast metabolic signaling
PURPOSE: Menopause is associated with an increased risk of estrogen receptor-positive (ER +) breast cancer. To characterize the metabolic shifts associated with reduced estrogen bioavailability on breast tissue, metabolomics was performed from ovary-intact and ovariectomized (OVX) female non-human p...
Autores principales: | Arnone, Alana A., Cline, J. Mark, Soto-Pantoja, David R., Cook, Katherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557185/ https://www.ncbi.nlm.nih.gov/pubmed/34448090 http://dx.doi.org/10.1007/s10549-021-06354-w |
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