KP772 overcomes multiple drug resistance in malignant lymphoma and leukemia cells in vitro by inducing Bcl-2-independent apoptosis and upregulation of Harakiri

Despite high cure rates in pediatric patients with acute leukemia, development of resistance limits the efficacy of antileukemic therapy. Tris(1,10-phenanthroline)tris(thiocyanato-κN)lanthanum(III) (KP772) is an experimental antineoplastic agent to which multidrug-resistant cell models have shown hy...

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Detalles Bibliográficos
Autores principales: Kater, Lisa, Kater, Benjamin, Jakupec, Michael A., Keppler, Bernhard K., Prokop, Aram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557194/
https://www.ncbi.nlm.nih.gov/pubmed/34617137
http://dx.doi.org/10.1007/s00775-021-01900-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557194/
https://www.ncbi.nlm.nih.gov/pubmed/34617137
http://dx.doi.org/10.1007/s00775-021-01900-9

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