Dose escalation biodistribution, positron emission tomography/computed tomography imaging and dosimetry of a highly specific radionuclide-labeled non-blocking nanobody

BACKGROUND: Immunotherapy is a valuable option for cancer treatment, and the curative effect of anti-PD-1/PD-L1 therapy correlates closely with PD-L1 expression levels. Positron emission tomography (PET) imaging of PD-L1 expression is feasible using (68)Ga-NOTA-Nb109 nanobody. (68)Ga-NOTA-Nb109 was...

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Detalles Bibliográficos
Autores principales: Yang, Yanling, Wang, Chao, Wang, Yan, Sun, Yan, Huang, Xing, Huang, Minzhou, Xu, Hui, Fan, Huaying, Chen, Daquan, Zhao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557220/
https://www.ncbi.nlm.nih.gov/pubmed/34718889
http://dx.doi.org/10.1186/s13550-021-00854-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557220/
https://www.ncbi.nlm.nih.gov/pubmed/34718889
http://dx.doi.org/10.1186/s13550-021-00854-y

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