Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei

BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare, slow-growing abdominal cancer with no efficacious treatment options in non-resectable and recurrent cases. Otherwise, rare activating mutations in the GNAS oncogene are remarkably frequent in PMP and the mutated gene product, guanine nucleotide-bin...

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Detalles Bibliográficos
Autores principales: Flatmark, Kjersti, Torgunrud, Annette, Fleten, Karianne G, Davidson, Ben, Juul, Hedvig V, Mensali, Nadia, Lund-Andersen, Christin, Inderberg, Else Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557294/
https://www.ncbi.nlm.nih.gov/pubmed/34711663
http://dx.doi.org/10.1136/jitc-2021-003109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557294/
https://www.ncbi.nlm.nih.gov/pubmed/34711663
http://dx.doi.org/10.1136/jitc-2021-003109

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