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Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes

The only definitive therapy for end‐stage liver disease is whole‐organ transplantation. The success of this intervention is severely limited by the complexity of the surgery, the cost of patient care, the need for long‐term immunosuppression, and the shortage of donor organs. In rodents and humans,...

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Detalles Bibliográficos
Autores principales: Tafaleng, Edgar N., Mukherjee, Amitava, Bell, Aaron, Morita, Kazutoyo, Guzman‐Lepe, Jorge, Haep, Nils, Florentino, Rodrigo M., Diaz‐Aragon, Ricardo, Frau, Carla, Ostrowska, Alina, Schultz, Joshua R., Martini, Paolo G. V., Soto‐Gutierrez, Alejandro, Fox, Ira J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557308/
https://www.ncbi.nlm.nih.gov/pubmed/34558820
http://dx.doi.org/10.1002/hep4.1763