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Comprehensive understanding of Tn5 insertion preference improves transcription regulatory element identification

Tn5 transposase, which can efficiently tagment the genome, has been widely adopted as a molecular tool in next-generation sequencing, from short-read sequencing to more complex methods such as assay for transposase-accessible chromatin using sequencing (ATAC-seq). Here, we systematically map Tn5 ins...

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Detalles Bibliográficos
Autores principales: Zhang, Houyu, Lu, Ting, Liu, Shan, Yang, Jianyu, Sun, Guohuan, Cheng, Tao, Xu, Jin, Chen, Fangyao, Yen, Kuangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557372/
https://www.ncbi.nlm.nih.gov/pubmed/34729473
http://dx.doi.org/10.1093/nargab/lqab094