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ParsVNN: parsimony visible neural networks for uncovering cancer-specific and drug-sensitive genes and pathways

Prediction of cancer-specific drug responses as well as identification of the corresponding drug-sensitive genes and pathways remains a major biological and clinical challenge. Deep learning models hold immense promise for better drug response predictions, but most of them cannot provide biological...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoqing, Huang, Kun, Johnson, Travis, Radovich, Milan, Zhang, Jie, Ma, Jianzhu, Wang, Yijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557386/
https://www.ncbi.nlm.nih.gov/pubmed/34729476
http://dx.doi.org/10.1093/nargab/lqab097