Cargando…
Mistranslation Reduces Mutation Load in Evolving Proteins through Negative Epistasis with DNA Mutations
Translational errors during protein synthesis cause phenotypic mutations that are several orders of magnitude more frequent than DNA mutations. Such phenotypic mutations may affect adaptive evolution through their interactions with DNA mutations. To study how mistranslation may affect the adaptive e...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557407/ https://www.ncbi.nlm.nih.gov/pubmed/34255074 http://dx.doi.org/10.1093/molbev/msab206 |