Fold Evolution before LUCA: Common Ancestry of SH3 Domains and OB Domains

SH3 and OB are the simplest, oldest, and most common protein domains within the translation system. SH3 and OB domains are β-barrels that are structurally similar but are topologically distinct. To transform an OB domain to a SH3 domain, β-strands must be permuted in a multistep and evolutionarily i...

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Detalles Bibliográficos
Autores principales: Alvarez-Carreño, Claudia, Penev, Petar I, Petrov, Anton S, Williams, Loren Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557408/
https://www.ncbi.nlm.nih.gov/pubmed/34383917
http://dx.doi.org/10.1093/molbev/msab240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557408/
https://www.ncbi.nlm.nih.gov/pubmed/34383917
http://dx.doi.org/10.1093/molbev/msab240

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