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Fold Evolution before LUCA: Common Ancestry of SH3 Domains and OB Domains
SH3 and OB are the simplest, oldest, and most common protein domains within the translation system. SH3 and OB domains are β-barrels that are structurally similar but are topologically distinct. To transform an OB domain to a SH3 domain, β-strands must be permuted in a multistep and evolutionarily i...
Autores principales: | Alvarez-Carreño, Claudia, Penev, Petar I, Petrov, Anton S, Williams, Loren Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557408/ https://www.ncbi.nlm.nih.gov/pubmed/34383917 http://dx.doi.org/10.1093/molbev/msab240 |
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