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An Ancient Clade of Penelope-Like Retroelements with Permuted Domains Is Present in the Green Lineage and Protists, and Dominates Many Invertebrate Genomes

Penelope-like elements (PLEs) are an enigmatic clade of retrotransposons whose reverse transcriptases (RTs) share a most recent common ancestor with telomerase RTs. The single ORF of canonical endonuclease (EN)+ PLEs encodes RT and a C-terminal GIY–YIG EN that enables intrachromosomal integration, w...

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Detalles Bibliográficos
Autores principales: Craig, Rory J, Yushenova, Irina A, Rodriguez, Fernando, Arkhipova, Irina R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557442/
https://www.ncbi.nlm.nih.gov/pubmed/34320655
http://dx.doi.org/10.1093/molbev/msab225