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Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells

BACKGROUND: IL-6 plays a pivotal role in resistance to chemotherapeutics, including lobaplatin. However, the underlying mechanisms are still unclear. This study was to investigate the changes in phosphoproteins and their related signaling pathways in the process of IL-6-induced chemoresistance to lo...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Wang, Huan, Li, Erliang, Wu, Yonghong, Wen, Yanhua, Li, Chenyu, Liao, Bo, Ma, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557500/
https://www.ncbi.nlm.nih.gov/pubmed/34717622
http://dx.doi.org/10.1186/s12935-021-02286-z