Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue

BACKGROUND: We previously reported that expression of a miR-138 mimic or knockdown of SIN3A in primary cultures of cystic fibrosis (CF) airway epithelia increased ΔF508-CFTR mRNA and protein levels, and partially restored CFTR-dependent chloride transport. Global mRNA transcript profiling in ΔF508-C...

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Detalles Bibliográficos
Autores principales: Strub, Matthew D., Gao, Long, Tan, Kai, McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557508/
https://www.ncbi.nlm.nih.gov/pubmed/34717611
http://dx.doi.org/10.1186/s12920-021-01106-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557508/
https://www.ncbi.nlm.nih.gov/pubmed/34717611
http://dx.doi.org/10.1186/s12920-021-01106-7

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