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Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis

BACKGROUND: Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there is a lack of universal measures of CAFs in colorectal cancer (CRC). The aim of this study was to assess the utility of a fi...

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Detalles Bibliográficos
Autores principales: Chen, Yu-feng, Yu, Zhao-liang, Lv, Min-yi, Cai, Ze-rong, Zou, Yi-feng, Lan, Ping, Wu, Xiao-jian, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557584/
https://www.ncbi.nlm.nih.gov/pubmed/34717544
http://dx.doi.org/10.1186/s10020-021-00402-3