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Cancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis
BACKGROUND: Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there is a lack of universal measures of CAFs in colorectal cancer (CRC). The aim of this study was to assess the utility of a fi...
Autores principales: | Chen, Yu-feng, Yu, Zhao-liang, Lv, Min-yi, Cai, Ze-rong, Zou, Yi-feng, Lan, Ping, Wu, Xiao-jian, Gao, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557584/ https://www.ncbi.nlm.nih.gov/pubmed/34717544 http://dx.doi.org/10.1186/s10020-021-00402-3 |
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