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Combined cART including Tenofovir Disoproxil, Emtricitabine, and Dolutegravir has potent therapeutic effects in HIV-1 infected humanized mice

HIV-1 reservoirs persist in the presence of combined antiretroviral therapy (cART). However, cART has transformed HIV-1 infection into a chronic disease marked by control of HIV-1 viral load and mortality reduction. Major challenges remain, including viral resistance upon termination of cART and per...

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Detalles Bibliográficos
Autores principales: Weichseldorfer, Matthew, Affram, Yvonne, Heredia, Alonso, Rikhtegaran-Tehrani, Zahra, Sajadi, Mohammad M., Williams, Sumiko P., Tagaya, Yutaka, Benedetti, Francesca, Ramadhani, Habib O., Denaro, Frank, Munawwar, Arshi, Bryant, Joseph, Zella, Davide, Reitz, Marvin, Romerio, Fabio, Latinovic, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557591/
https://www.ncbi.nlm.nih.gov/pubmed/34717655
http://dx.doi.org/10.1186/s12967-021-03120-w