Filling gaps of genome scaffolds via probabilistic searching optical maps against assembly graph

BACKGROUND: Optical maps record locations of specific enzyme recognition sites within long genome fragments. This long-distance information enables aligning genome assembly contigs onto optical maps and ordering contigs into scaffolds. The generated scaffolds, however, often contain a large amount o...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Wei, Guozheng, Wang, Bing, Ju, Fusong, Zhong, Yi, Shi, Zhuozheng, Sun, Shiwei, Bu, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557617/
https://www.ncbi.nlm.nih.gov/pubmed/34717539
http://dx.doi.org/10.1186/s12859-021-04448-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557617/
https://www.ncbi.nlm.nih.gov/pubmed/34717539
http://dx.doi.org/10.1186/s12859-021-04448-2

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