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Filling gaps of genome scaffolds via probabilistic searching optical maps against assembly graph

BACKGROUND: Optical maps record locations of specific enzyme recognition sites within long genome fragments. This long-distance information enables aligning genome assembly contigs onto optical maps and ordering contigs into scaffolds. The generated scaffolds, however, often contain a large amount o...

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Detalles Bibliográficos
Autores principales:	Huang, Bin, Wei, Guozheng, Wang, Bing, Ju, Fusong, Zhong, Yi, Shi, Zhuozheng, Sun, Shiwei, Bu, Dongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557617/ https://www.ncbi.nlm.nih.gov/pubmed/34717539 http://dx.doi.org/10.1186/s12859-021-04448-2

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