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Pharmacoresistant seizures and IDH mutation in low-grade gliomas

BACKGROUND: Many low-grade gliomas (LGG) harbor isocitrate dehydrogenase (IDH) mutations. Although IDH mutation is known to be epileptogenic, the rate of refractory seizures in LGG with IDH mutation vs wild-type had not been previously compared. We therefore compared seizure pharmacoresistance in ID...

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Detalles Bibliográficos
Autores principales: Correia, Carlos Eduardo, Umemura, Yoshie, Flynn, Jessica R, Reiner, Anne S, Avila, Edward K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557671/
https://www.ncbi.nlm.nih.gov/pubmed/34729486
http://dx.doi.org/10.1093/noajnl/vdab146