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Novel Small Molecule Growth Inhibitor Affecting Bacterial Outer Membrane Reduces Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection in Avian Model

Avian pathogenic Escherichia coli (APEC), a subgroup of extraintestinal pathogenic E. coli (ExPEC), causes colibacillosis in chickens and is reportedly implicated in urinary tract infections and meningitis in humans. A major limitation for the current ExPEC antibiotic therapy is the development of r...

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Detalles Bibliográficos
Autores principales: Kathayat, Dipak, Helmy, Yosra A., Deblais, Loic, Srivastava, Vishal, Closs, Gary, Khupse, Rahul, Rajashekara, Gireesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557866/
https://www.ncbi.nlm.nih.gov/pubmed/34468186
http://dx.doi.org/10.1128/Spectrum.00006-21