Cargando…

Novel Small Molecule Growth Inhibitor Affecting Bacterial Outer Membrane Reduces Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection in Avian Model

Avian pathogenic Escherichia coli (APEC), a subgroup of extraintestinal pathogenic E. coli (ExPEC), causes colibacillosis in chickens and is reportedly implicated in urinary tract infections and meningitis in humans. A major limitation for the current ExPEC antibiotic therapy is the development of r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kathayat, Dipak, Helmy, Yosra A., Deblais, Loic, Srivastava, Vishal, Closs, Gary, Khupse, Rahul, Rajashekara, Gireesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557866/ https://www.ncbi.nlm.nih.gov/pubmed/34468186 http://dx.doi.org/10.1128/Spectrum.00006-21

Ejemplares similares

Novel small molecules affecting cell membrane as potential therapeutics for avian pathogenic Escherichia coli
por: Kathayat, Dipak, et al.
Publicado: (2018)

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens
por: Helmy, Yosra A., et al.
Publicado: (2022)

Novel small molecule modulators of quorum sensing in avian pathogenic Escherichia coli (APEC)
por: Helmy, Yosra A., et al.
Publicado: (2018)

Genomic and Temporal Trends in Canine ExPEC Reflect Those of Human ExPEC
por: Elankumaran, Paarthiphan, et al.
Publicado: (2022)

Identification of Risk Factors for Invasive Extraintestinal Pathogenic Escherichia coli (ExPEC) Disease
por: Clarke, Erik, et al.
Publicado: (2021)

Efficacy of quorum sensing and growth inhibitors alone and in combination against avian pathogenic Escherichia coli infection in chickens
por: Helmy, Yosra A., et al.
Publicado: (2023)

Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC)
por: Lu, Hao, et al.
Publicado: (2020)

Small Molecule Adjuvants Potentiate Colistin Activity and Attenuate Resistance Development in Escherichia coli by Affecting pmrAB System
por: Kathayat, Dipak, et al.
Publicado: (2020)

Antibiotic Resistance and Virulence of Extraintestinal Pathogenic Escherichia coli (ExPEC) Vary According to Molecular Types
por: Duan, Yitao, et al.
Publicado: (2020)

Trends in ExPEC serogroups in the UK and their significance
por: Ciesielczuk, H., et al.
Publicado: (2016)

Novel Imidazole and Methoxybenzylamine Growth Inhibitors Affecting Salmonella Cell Envelope Integrity and its Persistence in Chickens
por: Deblais, Loïc, et al.
Publicado: (2018)

Author Correction: Novel Imidazole and Methoxybenzylamine Growth Inhibitors Affecting Salmonella Cell Envelope Integrity and its Persistence in Chickens
por: Deblais, Loïc, et al.
Publicado: (2019)

Novel Pathways Revealed in Bursa of Fabricius Transcriptome in Response to Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection
por: Sun, Hongyan, et al.
Publicado: (2015)

Spondylodiscitis in a healthy 12-year-old girl with Extraintestinal pathogenic Escherichia coli (ExPEC) bacteraemia
por: Gaschignard, J., et al.
Publicado: (2017)

New to Galleria mellonella: Modeling an ExPEC infection
por: Nathan, Sheila
Publicado: (2014)

Effect of Probiotic E. coli Nissle 1917 Supplementation on the Growth Performance, Immune Responses, Intestinal Morphology, and Gut Microbes of Campylobacter jejuni Infected Chickens
por: Helmy, Yosra A., et al.
Publicado: (2022)

Characterization of Escherichia coli in Dogs with Pyometra and the Influence of Diet on the Intestinal Colonization of Extraintestinal Pathogenic E. coli (ExPEC)
por: Xavier, Rafael Gariglio Clark, et al.
Publicado: (2022)

Hybrid Atypical Enteropathogenic and Extraintestinal Escherichia coli (aEPEC/ExPEC) BA1250 Strain: A Draft Genome
por: Munhoz, Danielle D., et al.
Publicado: (2021)

Overexpression of Outer Membrane Protein X (OmpX) Compensates for the Effect of TolC Inactivation on Biofilm Formation and Curli Production in Extraintestinal Pathogenic Escherichia coli (ExPEC)
por: Li, Binyou, et al.
Publicado: (2018)

Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages
por: Shaik, Sabiha, et al.
Publicado: (2017)

2712. Safety and Immunogenicity of two Doses of ExPEC4V Vaccine Against Extraintestinal Pathogenic Escherichia coli Disease in Healthy Adult Participants
por: B Smith, William, et al.
Publicado: (2019)

Genomics Analysis to Identify Multiple Genetic Determinants That Drive the Global Transmission of the Pandemic ST95 Lineage of Extraintestinal Pathogenic Escherichia coli (ExPEC)
por: Xia, Fufang, et al.
Publicado: (2022)

Genetic Characterization of ExPEC-Like Virulence Plasmids among a Subset of NMEC
por: Nicholson, Bryon A., et al.
Publicado: (2016)

Genomic Analysis of CTX-M-Group-1-Producing Extraintestinal Pathogenic E. coli (ExPEc) from Patients with Urinary Tract Infections (UTI) from Colombia
por: De La Cadena, Elsa, et al.
Publicado: (2020)

A cross-sectional study of the nasal and fecal microbiota of sows from different health status within six commercial swine farms
por: Arruda, Andreia G., et al.
Publicado: (2021)

TolC Promotes ExPEC Biofilm Formation and Curli Production in Response to Medium Osmolarity
por: Hou, Bo, et al.
Publicado: (2014)

Antimicrobial Resistance Profile and ExPEC Virulence Potential in Commensal Escherichia coli of Multiple Sources
por: Massella, Elisa, et al.
Publicado: (2021)

Avian Pathogenic Escherichia coli (APEC): An Overview of Virulence and Pathogenesis Factors, Zoonotic Potential, and Control Strategies
por: Kathayat, Dipak, et al.
Publicado: (2021)

Genetic diversity and multidrug resistance of phylogenic groups B2 and D in InPEC and ExPEC isolated from chickens in Central China
por: Lu, Qin, et al.
Publicado: (2022)

Bacteriocin-encoding genes and ExPEC virulence determinants are associated in human fecal Escherichia coli strains
por: Micenková, Lenka, et al.
Publicado: (2014)

Urinary tract infections attributed to diverse ExPEC strains in food animals: evidence and data gaps
por: Singer, Randall S.
Publicado: (2015)

Whole genome sequencing of an ExPEC that caused fatal pneumonia at a pig farm in Changchun, China
por: Kong, Ling-Cong, et al.
Publicado: (2017)

Overlapped Sequence Types (STs) and Serogroups of Avian Pathogenic (APEC) and Human Extra-Intestinal Pathogenic (ExPEC) Escherichia coli Isolated in Brazil
por: Maluta, Renato Pariz, et al.
Publicado: (2014)

Compound Prioritization through Meta-Analysis Enhances the Discovery of Antimicrobial Hits against Bacterial Pathogens
por: Deblais, Loic, et al.
Publicado: (2021)

High frequency of hybrid Escherichia coli strains with combined Intestinal Pathogenic Escherichia coli (IPEC) and Extraintestinal Pathogenic Escherichia coli (ExPEC) virulence factors isolated from human faecal samples
por: Lindstedt, Bjørn-Arne, et al.
Publicado: (2018)

A preliminary study on virulence factors & antimicrobial resistance in extra-intestinal pathogenic Escherichia coli (ExPEC) in Bangladesh
por: Fakruddin, Md., et al.
Publicado: (2013)

Correlation between the genomic o454-nlpD region polymorphisms, virulence gene equipment and phylogenetic group of extraintestinal Escherichia coli (ExPEC) enables pathotyping irrespective of host, disease and source of isolation
por: Ewers, Christa, et al.
Publicado: (2014)

Pandemic extra-intestinal pathogenic Escherichia coli (ExPEC) clonal group O6-B2-ST73 as a cause of avian colibacillosis in Brazil
por: Cunha, Marcos Paulo Vieira, et al.
Publicado: (2017)

Global Genomic Epidemiology of Escherichia coli (ExPEC) ST38 Lineage Revealed a Virulome Associated with Human Infections
por: Fonseca, Erica L., et al.
Publicado: (2022)

Molecular Characteristics of Extraintestinal Pathogenic E. coli (ExPEC), Uropathogenic E. coli (UPEC), and Multidrug Resistant E. coli Isolated from Healthy Dogs in Spain. Whole Genome Sequencing of Canine ST372 Isolates and Comparison with Human Isolates Causing Extraintestinal Infections
por: Flament-Simon, Saskia-Camille, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_imfmv3p47n4egg9eoma7mrm0c8