Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens

Transition metals are necessary cofactors and structural elements in living systems. Exposure to high concentrations of biologically important transition metals, such as zinc and copper, results in cell toxicity. At the infection site, the immune system deploys metal sorbent proteins (e.g., lactofer...

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Detalles Bibliográficos
Autores principales: Menghani, Sanjay V., Rivera, Angela, Neubert, Miranda, Hagerty, James R., Lewis, Lourdes, Galgiani, John N., Jolly, Emmitt R., Alvin, Joseph W., Johnson, Michael D. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557878/
https://www.ncbi.nlm.nih.gov/pubmed/34468162
http://dx.doi.org/10.1128/Spectrum.00778-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557878/
https://www.ncbi.nlm.nih.gov/pubmed/34468162
http://dx.doi.org/10.1128/Spectrum.00778-21

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