Cargando…

Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens

Transition metals are necessary cofactors and structural elements in living systems. Exposure to high concentrations of biologically important transition metals, such as zinc and copper, results in cell toxicity. At the infection site, the immune system deploys metal sorbent proteins (e.g., lactofer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Menghani, Sanjay V., Rivera, Angela, Neubert, Miranda, Hagerty, James R., Lewis, Lourdes, Galgiani, John N., Jolly, Emmitt R., Alvin, Joseph W., Johnson, Michael D. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557878/ https://www.ncbi.nlm.nih.gov/pubmed/34468162 http://dx.doi.org/10.1128/Spectrum.00778-21

Ejemplares similares

N,N-Dimethyldithiocarbamate Elicits Pneumococcal Hypersensitivity to Copper and Macrophage-Mediated Clearance
por: Menghani, Sanjay V., et al.
Publicado: (2022)

Heads or tails? Differential translational regulation in cercarial heads and tails of schistosome worms
por: Hagerty, James R., et al.
Publicado: (2019)

Ziram and Sodium N,N-Dimethyldithiocarbamate Inhibit Ubiquitin Activation through Intracellular Metal Transport and Increased Oxidative Stress in HEK293 Cells
por: Dennis, Kathleen E., et al.
Publicado: (2015)

Multiomic analysis of Schistosoma mansoni reveals unique expression profiles in cercarial heads and tails
por: Hagerty, James R., et al.
Publicado: (2021)

Prenatal Treatment of Mosaic Mice (Atp7a mo-ms) Mouse Model for Menkes Disease, with Copper Combined by Dimethyldithiocarbamate (DMDTC)
por: Lenartowicz, Małgorzata, et al.
Publicado: (2012)

Characterization of Schistosome Sox Genes and Identification of a Flatworm Class of Sox Regulators
por: Wood, Stephanie, et al.
Publicado: (2023)

Electrical conductivity and thermodynamic studies on Sodium Dimethyldithiocarbamate in non aqueous solvents Dimethylformamide (DMF), at different temperatures
por: Hammad, W. A., et al.
Publicado: (2022)

Author Correction: Electrical conductivity and thermodynamic studies on Sodium Dimethyldithiocarbamate in non aqueous solvents Dimethylformamide (DMF), at different temperatures
por: Hammad, W. A., et al.
Publicado: (2023)

Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
por: Hirono, I., et al.
Publicado: (1982)

Hsp70 May Be a Molecular Regulator of Schistosome Host Invasion
por: Ishida, Kenji, et al.
Publicado: (2016)

Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors
por: O’Brien, Henrik, et al.
Publicado: (2020)

Novel dithiocarbamate derivatives are effective copper-dependent antimicrobials against Streptococcal species
por: Menghani, Sanjay V., et al.
Publicado: (2023)

Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
por: Milligan, John N., et al.
Publicado: (2011)

Identification and Characterization of a Mef2 Transcriptional Activator in Schistosome Parasites
por: Milligan, John N., et al.
Publicado: (2012)

LncRNAs Are Differentially Expressed between Wildtype and Cell Line Strains of African Trypanosomes
por: Kim, Hyung Chul, et al.
Publicado: (2022)

Polyethyleneimine Mediated DNA Transfection in Schistosome Parasites and Regulation of the WNT Signaling Pathway by a Dominant-Negative SmMef2
por: Liang, Shuang, et al.
Publicado: (2013)

μ-Cyanido-κ(2) C:N-dicyanido-κ(2) C-bis(N-ethylethylenediamine-κ(2) N,N′)copper(II)copper(I)
por: Corfield, Peter W. R., et al.
Publicado: (2014)

Evaluation of Schistosome Promoter Expression for Transgenesis and Genetic Analysis
por: Liang, Shuang, et al.
Publicado: (2014)

Correction: Evaluation of Schistosome Promoter Expression for Transgenesis and Genetic Analysis
por: Liang, Shuang, et al.
Publicado: (2019)

LncRNAs in molluscan and mammalian stages of parasitic schistosomes are developmentally-regulated and coordinately expressed with protein-coding genes
por: Kim, Hyung Chul, et al.
Publicado: (2020)

Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice
por: Hatta, Masato, et al.
Publicado: (2007)

Characterization of the Upper Respiratory Tract Microbiomes of Patients with Pandemic H1N1 Influenza
por: Chaban, Bonnie, et al.
Publicado: (2013)

Mechanistic insights into copper-catalyzed aerobic oxidative coupling of N–N bonds
por: Ryan, Michael C., et al.
Publicado: (2019)

Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis
por: Jolly, Emmitt R, et al.
Publicado: (2005)

Immunolocalization of Anti-Hsf1 to the Acetabular Glands of Infectious Schistosomes Suggests a Non-Transcriptional Function for This Transcriptional Activator
por: Ishida, Kenji, et al.
Publicado: (2014)

catena-Poly[[[(diethylenetriamine-κ(3) N,N′,N′′)copper(II)]-μ-cyanido-κ(2) C:N] perchlorate]
por: Corfield, Peter W. R., et al.
Publicado: (2012)

Dysplasia of the Upper Aerodigestive Tract Squamous Epithelium
por: Eversole, Lewis Roy
Publicado: (2009)

Copper-catalyzed aminooxygenation of styrenes with N-fluorobenzenesulfonimide and N-hydroxyphthalimide derivatives
por: Li, Yan, et al.
Publicado: (2015)

Upper respiratory tract infections
por: Jain, Neemisha, et al.
Publicado: (2001)

Tight N-observable uncertainty relations and their experimental demonstrations
por: Chen, Zhi-Xin, et al.
Publicado: (2019)

Bis[N-(2-hydroxyethyl)-N-methylglycinato]copper(II)
por: Buvaylo, Elena A., et al.
Publicado: (2008)

Bromidobis(N,N′-diphenylthiourea-κS)copper(I) monohydrate
por: Mufakkar, Muhammad, et al.
Publicado: (2009)

Bis(N,N′-diphenylthiourea)iodidocopper(I) monohydrate
por: Jia, Li, et al.
Publicado: (2008)

Copper(II) N,N,O-Chelating Complexes as Potential Anticancer Agents
por: Peña, Quim, et al.
Publicado: (2021)

Prognostic role of expression of N-cadherin in patients with upper tract urothelial carcinoma: a multi-institutional study
por: Abufaraj, Mohammad, et al.
Publicado: (2016)

Bis(acetato-κO)[N,N,N′,N′-tetramethylethane-1,2-diamine-κ(2) N,N′]copper(II)
por: Slootweg, J. Chris, et al.
Publicado: (2008)

catena-Poly[[(1,10-phenanthroline-κ(2) N,N′)copper(I)]-μ-thiocyanato-κ(2) N:S-[(1,10-phenanthroline-κ(2) N,N′)copper(I)]-μ-cyanido-κ(2) N:C]
por: Zhao, Jun, et al.
Publicado: (2008)

Dynamics and Design Principles of a Basic Regulatory Architecture Controlling Metabolic Pathways
por: Chin, Chen-Shan, et al.
Publicado: (2008)

(N,N-Diethyldithiocarbamato-κ(2) S,S′)iodido(1,10-phenanthroline-κ(2) N,N′)copper(II)
por: Fan, Le-Qing, et al.
Publicado: (2009)

Aqua(azido)[N-(pyridin-2-ylcarbonyl)pyridine-2-carboxamido-κ(3) N,N′,N′′]copper(II)
por: Bruda, Sandra, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_c3svusa7rfumkevt3hd14jj7f9