Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy

The therapeutic repertoire for tuberculosis (TB) remains limited despite the existence of many TB drugs that are highly active in in vitro models and possess clinical utility. Underlying the lack of efficacy in vivo is the inability of TB drugs to penetrate microenvironments inhabited by the causati...

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Detalles Bibliográficos
Autores principales: Tanner, Lloyd, Mashabela, Gabriel T., Omollo, Charles C., de Wet, Timothy J., Parkinson, Christopher J., Warner, Digby F., Haynes, Richard K., Wiesner, Lubbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557888/
https://www.ncbi.nlm.nih.gov/pubmed/34585951
http://dx.doi.org/10.1128/Spectrum.00434-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557888/
https://www.ncbi.nlm.nih.gov/pubmed/34585951
http://dx.doi.org/10.1128/Spectrum.00434-21

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