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Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis

Phosphopantetheinyl hydrolase, PptH (Rv2795c), is a recently discovered enzyme from Mycobacterium tuberculosis that removes 4′-phosphopantetheine (Ppt) from holo-carrier proteins (CPs) and thereby opposes the action of phosphopantetheinyl transferases (PPTases). PptH is the first structurally charac...

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Detalles Bibliográficos
Autores principales: Pandey, Shilpika, Singh, Amrita, Yang, Guangli, d’Andrea, Felipe B., Jiang, Xiuju, Hartman, Travis E., Mosior, John W., Bourland, Ronnie, Gold, Ben, Roberts, Julia, Geiger, Annie, Tang, Su, Rhee, Kyu, Ouerfelli, Ouathek, Sacchettini, James C., Nathan, Carl F., Burns-Huang, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557913/
https://www.ncbi.nlm.nih.gov/pubmed/34550010
http://dx.doi.org/10.1128/Spectrum.00928-21