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Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis
Phosphopantetheinyl hydrolase, PptH (Rv2795c), is a recently discovered enzyme from Mycobacterium tuberculosis that removes 4′-phosphopantetheine (Ppt) from holo-carrier proteins (CPs) and thereby opposes the action of phosphopantetheinyl transferases (PPTases). PptH is the first structurally charac...
Autores principales: | Pandey, Shilpika, Singh, Amrita, Yang, Guangli, d’Andrea, Felipe B., Jiang, Xiuju, Hartman, Travis E., Mosior, John W., Bourland, Ronnie, Gold, Ben, Roberts, Julia, Geiger, Annie, Tang, Su, Rhee, Kyu, Ouerfelli, Ouathek, Sacchettini, James C., Nathan, Carl F., Burns-Huang, Kristin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557913/ https://www.ncbi.nlm.nih.gov/pubmed/34550010 http://dx.doi.org/10.1128/Spectrum.00928-21 |
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