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Patient-Tailored Levothyroxine Dosage with Pharmacokinetic/Pharmacodynamic Modeling: A Novel Approach After Total Thyroidectomy

Background: After seven decades of levothyroxine (LT4) replacement therapy, dosage adjustment still takes several months. We have developed a decision aid tool (DAT) that models LT4 pharmacometrics and enables patient-tailored dosage. The aim of this was to speed up dosage adjustments for patients a...

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Detalles Bibliográficos
Autores principales: Brun, Vegard Heimly, Eriksen, Amund H., Selseth, Ruth, Johansson, Kenth, Vik, Renate, Davidsen, Benedicte, Kaut, Michal, Hellemo, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558060/
https://www.ncbi.nlm.nih.gov/pubmed/33980057
http://dx.doi.org/10.1089/thy.2021.0125