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Patient-Tailored Levothyroxine Dosage with Pharmacokinetic/Pharmacodynamic Modeling: A Novel Approach After Total Thyroidectomy
Background: After seven decades of levothyroxine (LT4) replacement therapy, dosage adjustment still takes several months. We have developed a decision aid tool (DAT) that models LT4 pharmacometrics and enables patient-tailored dosage. The aim of this was to speed up dosage adjustments for patients a...
Autores principales: | Brun, Vegard Heimly, Eriksen, Amund H., Selseth, Ruth, Johansson, Kenth, Vik, Renate, Davidsen, Benedicte, Kaut, Michal, Hellemo, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558060/ https://www.ncbi.nlm.nih.gov/pubmed/33980057 http://dx.doi.org/10.1089/thy.2021.0125 |
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