Human Endogenous Retrovirus Type W Envelope from Multiple Sclerosis Demyelinating Lesions Shows Unique Solubility and Antigenic Characteristics

In multiple sclerosis (MS), human endogenous retrovirus W family (HERV-W) envelope protein, pHERV-W ENV, limits remyelination and induces microglia-mediated neurodegeneration. To better understand its role, we examined the soluble pHERV-W antigen from MS brain lesions detected by specific antibodies...

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Detalles Bibliográficos
Autores principales: Charvet, Benjamin, Pierquin, Justine, Brunel, Joanna, Gorter, Rianne, Quétard, Christophe, Horvat, Branka, Amor, Sandra, Portoukalian, Jacques, Perron, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558138/
https://www.ncbi.nlm.nih.gov/pubmed/33770381
http://dx.doi.org/10.1007/s12250-021-00372-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558138/
https://www.ncbi.nlm.nih.gov/pubmed/33770381
http://dx.doi.org/10.1007/s12250-021-00372-0

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