Risk assessment in deferred and recovered donors

Serologic testing and Donor Risk Assessment Interview (DRAI) combined have made tissue transplantation a frequent and safe modality for a variety of trauma and disease conditions. Donate Life America reports 30,000 tissue donors providing more than 1,750,000 tissue transplants annually. This study o...

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Autores principales: Heck, Ellen, Corder, Valerie, Urban, Jill, Petroll, Matthew, Timmons, William, Cavanaugh, Dwight
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558152/
https://www.ncbi.nlm.nih.gov/pubmed/33742287
http://dx.doi.org/10.1007/s10561-021-09909-9
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author Heck, Ellen
Corder, Valerie
Urban, Jill
Petroll, Matthew
Timmons, William
Cavanaugh, Dwight
author_facet Heck, Ellen
Corder, Valerie
Urban, Jill
Petroll, Matthew
Timmons, William
Cavanaugh, Dwight
author_sort Heck, Ellen
collection PubMed
description Serologic testing and Donor Risk Assessment Interview (DRAI) combined have made tissue transplantation a frequent and safe modality for a variety of trauma and disease conditions. Donate Life America reports 30,000 tissue donors providing more than 1,750,000 tissue transplants annually. This study of 188 potential donor cases addresses issues of risk assessment in a medical examiner population in a metropolitan area, where serologic testing of deferred potential donors were compared with the DRAI screening, which determined the suitability or non-suitability for tissue procurement. Such serologic testing of deferred cases is not usually available in evaluating screening processes. This comparison gives insight into the effectiveness of the DRAI screening in deferring potential serology reactive donors. Results show in 65 cases how the DRAI screening eliminates most, but not all of the serologically reactive donors identified post recovery. The result emphasizes the need for the combined process of DRAI screening and testing to assure transplantation safety.
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spelling pubmed-85581522021-11-15 Risk assessment in deferred and recovered donors Heck, Ellen Corder, Valerie Urban, Jill Petroll, Matthew Timmons, William Cavanaugh, Dwight Cell Tissue Bank Article Serologic testing and Donor Risk Assessment Interview (DRAI) combined have made tissue transplantation a frequent and safe modality for a variety of trauma and disease conditions. Donate Life America reports 30,000 tissue donors providing more than 1,750,000 tissue transplants annually. This study of 188 potential donor cases addresses issues of risk assessment in a medical examiner population in a metropolitan area, where serologic testing of deferred potential donors were compared with the DRAI screening, which determined the suitability or non-suitability for tissue procurement. Such serologic testing of deferred cases is not usually available in evaluating screening processes. This comparison gives insight into the effectiveness of the DRAI screening in deferring potential serology reactive donors. Results show in 65 cases how the DRAI screening eliminates most, but not all of the serologically reactive donors identified post recovery. The result emphasizes the need for the combined process of DRAI screening and testing to assure transplantation safety. Springer Netherlands 2021-03-19 2021 /pmc/articles/PMC8558152/ /pubmed/33742287 http://dx.doi.org/10.1007/s10561-021-09909-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Heck, Ellen
Corder, Valerie
Urban, Jill
Petroll, Matthew
Timmons, William
Cavanaugh, Dwight
Risk assessment in deferred and recovered donors
title Risk assessment in deferred and recovered donors
title_full Risk assessment in deferred and recovered donors
title_fullStr Risk assessment in deferred and recovered donors
title_full_unstemmed Risk assessment in deferred and recovered donors
title_short Risk assessment in deferred and recovered donors
title_sort risk assessment in deferred and recovered donors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558152/
https://www.ncbi.nlm.nih.gov/pubmed/33742287
http://dx.doi.org/10.1007/s10561-021-09909-9
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