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Quality control in scRNA-Seq can discriminate pacemaker cells: the mtRNA bias

Single-cell RNA-sequencing (scRNA-seq) provides high-resolution insights into complex tissues. Cardiac tissue, however, poses a major challenge due to the delicate isolation process and the large size of mature cardiomyocytes. Regardless of the experimental technique, captured cells are often impair...

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Detalles Bibliográficos
Autores principales: Galow, Anne-Marie, Kussauer, Sophie, Wolfien, Markus, Brunner, Ronald M., Goldammer, Tom, David, Robert, Hoeflich, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558157/
https://www.ncbi.nlm.nih.gov/pubmed/34427691
http://dx.doi.org/10.1007/s00018-021-03916-5