Genomic profiling using the UltraSEEK panel identifies discordancy between paired primary and breast cancer brain metastases and an association with brain metastasis-free survival

PURPOSE: Brain metastases (BM) are an increasing clinical problem. This study aimed to assess paired primary breast cancers (BC) and BM for aberrations within TP53, PIK3CA, ESR1, ERBB2 and AKT utilising the MassARRAY® UltraSEEK® technology (Agena Bioscience, San Diego, USA). METHODS: DNA isolated fr...

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Detalles Bibliográficos
Autores principales: Giannoudis, Athina, Sartori, Alexander, Eastoe, Lee, Zakaria, Rasheed, Charlton, Christopher, Hickson, Nicholas, Platt-Higgins, Angela, Rudland, Philip S., Irwin, Darryl, Jenkinson, Michael D., Palmieri, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Preclinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558178/
https://www.ncbi.nlm.nih.gov/pubmed/34499316
http://dx.doi.org/10.1007/s10549-021-06364-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558178/
https://www.ncbi.nlm.nih.gov/pubmed/34499316
http://dx.doi.org/10.1007/s10549-021-06364-8

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