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Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells

Hepatocellular carcinoma (HCC) is one of the most difficult cancer types to treat. Liver cancer is often diagnosed at late stages and therapeutic treatment is frequently accompanied by development of multidrug resistance. This leads to poor outcomes for cancer patients. Understanding the fundamental...

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Detalles Bibliográficos
Autores principales: Wegner, Marthe-Susanna, Schömel, Nina, Olzomer, Ellen M., Trautmann, Sandra, Olesch, Catherine, Byrne, Frances L., Brüne, Bernhard, Gurke, Robert, Ferreirós, Nerea, Weigert, Andreas, Geisslinger, Gerd, Hoehn, Kyle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558193/
https://www.ncbi.nlm.nih.gov/pubmed/34626204
http://dx.doi.org/10.1007/s00018-021-03958-9