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Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells
Hepatocellular carcinoma (HCC) is one of the most difficult cancer types to treat. Liver cancer is often diagnosed at late stages and therapeutic treatment is frequently accompanied by development of multidrug resistance. This leads to poor outcomes for cancer patients. Understanding the fundamental...
Autores principales: | Wegner, Marthe-Susanna, Schömel, Nina, Olzomer, Ellen M., Trautmann, Sandra, Olesch, Catherine, Byrne, Frances L., Brüne, Bernhard, Gurke, Robert, Ferreirós, Nerea, Weigert, Andreas, Geisslinger, Gerd, Hoehn, Kyle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558193/ https://www.ncbi.nlm.nih.gov/pubmed/34626204 http://dx.doi.org/10.1007/s00018-021-03958-9 |
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