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Control of the eIF4E activity: structural insights and pharmacological implications

The central role of eukaryotic translation initiation factor 4E (eIF4E) in controlling mRNA translation has been clearly assessed in the last decades. eIF4E function is essential for numerous physiological processes, such as protein synthesis, cellular growth and differentiation; dysregulation of it...

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Detalles Bibliográficos
Autores principales: Romagnoli, Alice, D’Agostino, Mattia, Ardiccioni, Chiara, Maracci, Cristina, Motta, Stefano, La Teana, Anna, Di Marino, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558276/
https://www.ncbi.nlm.nih.gov/pubmed/34541613
http://dx.doi.org/10.1007/s00018-021-03938-z